A comparison of ornithine decarboxylases from normal and SV40-transformed 3T3 mouse fibroblasts
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چکیده
منابع مشابه
Expression of a protein tyrosine phosphatase in normal and v-src- transformed mouse 3T3 fibroblasts
A rat cDNA encoding a 51-kD protein tyrosine phosphatase (PTP1) was cloned into a mammalian expression vector and transfected into normal and v-src-transformed mouse NIH 3T3 fibroblasts. In the stable subclones isolated, PTP1 expression at the mRNA level was elevated twofold to 25-fold. The highest constitutive level of phosphotyrosine-specific dephosphorylating activity observed without cytoto...
متن کاملStudies on the glycosphingolipids of normal and virally transformed 3T3 mouse fibroblasts.
The neutral glycosphingolipids and the gangliosides of normal 3T3 mouse fibroblasts, one polyoma-transformed, and three SV40-transformed clonal isolates have been examined. The normal 3T3 cells contained monoand dihexosylceramides and a complex pattern of gangliosides. The carbohydrate and fatty acid compositions of these neutral glycosphingolipids and of the principal gangliosides were determi...
متن کاملComparison of effects of simple sugars on 3T3 mouse fibroblasts and 3T3 cells transformed by infection with oncogenic viruses.
by oncogenic viruses [simian virus 40 (SV40) or jx)lyoma virus or sequential infection with both viruses], their susceptibility to changes caused by L-fucose was greatly reduced. Thus, virustransformed cells grown in the presence of L-fucose showed much less of a change in the morphology of individual cells, their pattern of association, their rate of growth, and incorporation of protein and RN...
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The effect of ascorbate on the glycosaminoglycans synthesized by normal and simian virus 40(SV40)-transformed human skin fibroblasts was examined. Cells were incubated in the presence or absence of ascorbate, and radiolabelled with [3H]glucosamine and [35S]sulphate for 48 h, 3 days after reaching confluence. Glycosaminoglycans were analysed in the medium, a collagenase extract, and in the tryps...
متن کاملThe effect of SV40 transformation on the chromosomal proteins of 3T3 mouse embryo fibroblasts.
The composition and metabolism of chromosomal proteins-histones and nonhistones chromosomal proteins-were examined in normal and SV40 transformed 3T3 mouse cells. Variations were observed, many of which were similar to those previously reported for normal and SV40 transformed W138 human diploid fibroblasts. The possible implications of these viral induced changes in the protein component of the...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1981
ISSN: 0264-6021
DOI: 10.1042/bj1940229